Women's Nike Run Defy

Colorway: White/Smoke Grey/Black · Style code: HM9593-101 · Release date: July 14, 2026 at 10:00 AM ET · Price: $65 · Availability: Sold out at retail

Where to buy: Nike

More colorways: Women's Nike Run Defy (HM9593-003) · Women's Nike Run Defy (HM9593-100) · Women's Nike Run Defy (HM9593-001) · Women's Nike Run Defy (HM9593-109) · Women's Nike Run Defy (HM9593-122)

About the Women's Nike Run Defy

The women's Nike Run Defy keeps most of its White/Smoke Grey/Black palette above a white midsole, using narrow grey lines to add detail around the toe and quarter. A long black-outlined Swoosh overlaps that pattern, while the heel and collar stay largely pale. The black outsole is visible at the toe and heel from the side, creating small dark edges beneath the otherwise light runner. Conventional laces and a low padded-looking opening complete the upper's simple arrangement.

Mesh provides the upper material, and a foam midsole supplies the cushioning. Nike specifies flex grooves and a waffle outsole with additional rubber in contact areas. The photographed underside separates the black forefoot and heel sections around a pale central waist. Listed specifications include a 10 mm drop. The regular US price was $65 on September 22, 2026.